Profile: Asian Americans - U.S. Department of Health and Human Services (HHS) Office of Minority Health (OMH)This racial group is defined as people having origins in any of the original peoples of the East Asia, Southeast Asia, or the Indian subcontinent. According to the 2019 Census Bureau population estimate, there are 18.9 million Asian Americans, alone, living in the United States. Asian Americans account for 5.7 percent of the nation's population. In 2019, the following states had the largest Asian American populations: California, New York, Texas, New Jersey, Illinois, Washington, Florida, Virginia, Hawaii, Massachusetts.