PLOS ONEThe world’s first multidisciplinary Open Access journal, PLOS ONE accepts scientifically rigorous research, regardless of novelty. PLOS ONE’s broad scope provides a platform to publish primary research, including interdisciplinary and replication studies as well as negative results. The journal’s publication criteria are based on high ethical standards and the rigor of the methodology and conclusions reported.Features reports of original research from the natural sciences, medical research, engineering, as well as the related social sciences and humanities that will contribute to the base of scientific knowledge. By not excluding research on the basis of subject area, PLOS ONE facilitates the discovery of connections between research whether within or between disciplines.